Gene expression neighborhoods
نویسندگان
چکیده
The finding that neighboring eukaryotic genes are often expressed in similar patterns suggests the involvement of chromatin domains in the control of genes within a genomic neighborhood.
منابع مشابه
Connected gene neighborhoods in prokaryotic genomes.
A computational method was developed for delineating connected gene neighborhoods in bacterial and archaeal genomes. These gene neighborhoods are not typically present, in their entirety, in any single genome, but are held together by overlapping, partially conserved gene arrays. The procedure was applied to comparing the orders of orthologous genes, which were extracted from the database of Cl...
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Traditionally eukaryotic genes are considered independently expressed under the control of their promoters and cis-regulatory domains. However, recent studies in worms, flies, mice and humans have shown that genes co-habiting a chromatin domain or "genomic neighborhood" are frequently co-expressed. Often these co-expressed genes neither constitute part of an operon nor function within the same ...
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عنوان ژورنال:
- Journal of Biology
دوره 1 شماره
صفحات -
تاریخ انتشار 2002